“REFUEL” Active Women’s Study II:

The Impact of Increased Caloric Intake on Bone Health and Menstrual Cyclicity in Energy Deficient Exercising Women
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  • Why is this important?
  • Study Summary
  • Do I qualify?
  • Procedure for Volunteering
  • Flow Chart
  • Study Phases
    • Qualification Phase
    • Baseline Phase
    • Experimental Phase
    • Post-study Phase
  • FAQs
  • Who We Are

Why is this important? Are there any risks?

Benefits to Me, the Participant:

  • You will have bone density, hormone levels, body fat, and fitness levels measured.
  • You will receive information about the importance of adequate food intake for reproductive health.
  • You will receive nutrition and diet analysis, and measures of daily energy intake and expenditure.
  • In return for your participation, you will receive a complete report of your scores on the tests and procedures, and an explanation of the meaningfulness of the results of this study from the study doctor.

Benefits to Society

  • By participating in this research, you will help increase our knowledge of how energy levels and diet affect the menstrual cycle and bones.
  • These results may help doctors and scientists understand how they can prevent and reverse menstrual problems and the bone loss that occurs in some women who exercise.

Risks

  • There are risks associated with study participation, which include but are not limited to:
    • The risks associated with single blood samples obtained with a needle and syringe may for example: local discomfort, occasional dizziness and nausea, and black and blue marks.
    • The discomfort associated with increasing the amount of food you eat - for those volunteers with irregular or absent menstrual cycles who are in the intervention group required to eat more calories, or for EAMD Controls who elect to increase their calories.
    • Frequent lab visits, repeated testing, collecting one’s urine for the duration of the study may represent inconveniences for participant
  • A full explanation of all the risks associated with the study is available in the informed consent.
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